Covid-19: Patients report recurrence of symptoms after Paxlovid | Health

Paxlovid, Covid-19 vaccine
Published: commons – 04/27/2022

Paxlovid, Covid-19 vaccine

According to Pfizer oral vaccine for Covid-19 has been widely used in the US, with nearly 3 million boxes available for pharmacies, some patients have reported symptoms of the The disease returned after the improvement encountered with the treatment of the disease.

Approved small doses of Covid, Paxlovid, including the antibiotics nirmatrelvir and ritonavir, used it approved by the Ministry of Health in the Brazilian Unified Health System (SUS) last Sunday. It is the first drug of its kind licensed in the country

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What recurrence of Covid symptoms soon after treatment with Paxlovid?

Dozens of people have reported recovery from Covid symptoms on social media or to the American health care provider after taking Paxlovid, but Pfizer reports the experience is unknown. rare.

According to the manufacturer, of the more than 300,000 patients cared for after five days of treatment, 1 in 3,000 (0.03%) reported recovery after taking the drug.

That is a lower cost than what Pfizer saw in its clinical trial, where about 2% of participants experienced recovery from the disease after completing treatment.

Pfizer studies have shown that recovery may be a long-term Covid, as a similar number of placebo recipients also experience a recovery from infectious diseases.

Why do these diseases occur?

The reason is not yet known. Some doctors said that because the drug fights the disease so quickly, some patients’ immune system to Covid will remain, allowing the disease to recur. Others have suggested that there may be a lack of awareness about the well-being of victims.

Pfizer director of development, William Pao, said it could be interfering with the disease itself, not Paxlovid, because the results were seen in patients who received the drug and those who did not. not yet.

The Food and Drug Administration (FDA), an agency similar to Anvisa in Brazil, also said it was unsure whether the reversal would affect Paxlovid.

Do I need to take a second dose of Paxlovid after recovery?

No, according to the FDA. The agency said last week that there was no evidence of benefit for a second dose of five days or for a 10-day cycle.

Pfizer shows something else. Director Albert Bourla said patients and physicians had told the company that the second five-day cycle of Paxlovid had eliminated the virus. Mikael Dolsten, chief executive of the company’s researchers, recently said that some immunosuppressants “can carry the virus for a long, long time” and may need to travel. or used for a long time.

The FDA added that the reversal did not change Paxlovid’s ability to reduce hospitalizations and deaths.

Who is eligible for Paxlovid?

Eligibility for Paxlovid varies from country to country. In Brazil, it has been reported for mild and moderate illnesses, who have not been hospitalized or need extra oxygen, but are at higher risk of complications, in people over 65 years of age. or have immunizations. You also need to be screened for Covid-19.

Does Medication Work Against Covid for a Long Time?

Paxlovid is not allowed to treat a chronic, unreliable long-term condition called Covid. However, there are recent case studies of patients with long-term Covid who experience positive symptoms after taking Paxlovid.

* With data from Reuters

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